This research paper examines the effectiveness of different machine learning (ML) models in analyzing how library usage influences the academic performance of Thammasat University students. By leveraging a comprehensive dataset that contains library interactions such as library of things (LoT) services, book borrowing and returning, and space services, this study evaluates five ML models: decision tree, k-nearest neighbors, Naïve Bayes, random forest, and support vector machine. The primary goal is to identify which library services and facilities significantly impact student success to provide actionable insights for customizing library offerings and enhancing academic outcomes. Results were that the decision tree model was particularly effective, delivering precise, reliable classification of factors affecting student academic performance into training data and data testing, using the 10-fold cross-validation procedure. These findings help demonstrate practical applications of ML in educational contexts and facilitate library strategic planning and management.